The Connection Between Mold and Autoimmune Disorders
- Colin Emmons
- May 17, 2025
- 2 min read

Mold exposure is commonly associated with allergies, asthma, and respiratory irritation—but its impact on the immune system can go much deeper. For individuals with autoimmune disorders, or those genetically predisposed to them, mold may play a significant role in triggering or worsening symptoms.
In this post, we’ll explore how mold can affect immune function, why it’s particularly dangerous for autoimmune sufferers, and what steps you can take to protect your health and home.
What Are Autoimmune Disorders?
Autoimmune disorders occur when the body’s immune system mistakenly attacks its own tissues. Conditions like lupus, rheumatoid arthritis, multiple sclerosis, Hashimoto’s thyroiditis, and others fall into this category. While the exact causes are still being researched, genetics, environmental triggers, and chronic inflammation all play a role.
How Mold Impacts the Immune System
Mold produces microscopic spores and, in some cases, mycotoxins—toxic compounds that can be harmful when inhaled or absorbed over time. In susceptible individuals, these contaminants can:
Trigger chronic inflammation, leading to tissue damage
Disrupt the gut microbiome, where much of the immune system is regulated
Contribute to immune dysregulation, increasing the risk of autoimmune flare-ups
Overwhelm the body’s natural detox pathways, leading to toxic buildup
Prolonged exposure to indoor mold can keep the immune system in a constant state of stress, which is especially problematic for people with autoimmune conditions or compromised immunity.
Real-World Symptoms and Experiences
While more research is needed, many people with autoimmune disorders report a worsening of symptoms after being exposed to mold. These can include:
Increased joint or muscle pain
Brain fog and fatigue
Digestive issues
Skin rashes or sensitivity
Heightened immune reactivity
For some, removing mold from their environment leads to a noticeable improvement in symptoms and quality of life.
What You Can Do
If you or a loved one has an autoimmune disorder and suspects mold could be a contributing factor, here are steps to consider:
Inspect Your Home – Focus on high-risk areas like basements, attics, crawl spaces, and around plumbing.
Get Air Quality Testing – Professional testing can identify mold spores and mycotoxins that may not be visible.
Remediate the Source – Proper mold remediation includes containment, HEPA filtration, and removal of affected materials.
Reduce Indoor Humidity – Use dehumidifiers and ensure proper ventilation to prevent future mold growth.
Support Immune Recovery – Work with a functional medicine provider or specialist to help your body recover post-exposure.
Final Thoughts
The link between mold and autoimmune disorders is an emerging area of concern that deserves attention. While not everyone exposed to mold will develop autoimmune symptoms, those with existing conditions may be particularly vulnerable to its effects.
At Above All Mold Removal, we help families across Massachusetts create safer, healthier living spaces by eliminating mold at the source. If you’re managing an autoimmune condition and suspect mold could be a factor, don’t wait—contact us today for an inspection or air quality test.




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